Jaroslaw Harezlak



Department of Biostatistics,

Harvard School of Public Health, Boston, MA, USA

Research Fellow (Biostatistics)






Harvard University, Cambridge, MA

University of British Columbia, Vancouver, BC, Canada

Ph.D. (Biostatistics)

M.Sc. (Statistics)







Simon Fraser University, Burnaby, BC, Canada

B.Sc. (Mathematics)






Department of Biostatistics, Indiana University Fairbanks School of Public Health

Department of Biostatistics, Indiana University School of Medicine


Assistant Professor


Assistant Professor







Division of Biostatistics, Indiana University School of Medicine

Assistant Professor









Department of Mathematics and Statistics, University of Wollongong, Wollongong, Australia

Division of Biostatistics, Indiana University School of Medicine, Indianapolis, IN

Coquitlam College, Coquitlam, BC, Canada

Visiting Professor











Functional data analysis, semiparametric regression, brain imaging and ecological momentary assessment.

  1. *Randolph, T.W., Harezlak, J., Feng, Z. "Structured penalties for functional linear models---partially empirical eigenvectors for regression" Electronic Journal of Statistics 2012, Vol. 6, No.0, 323-353. NIHMSID: NIHMS368253
  1. *Aalsma, M.C., Blythe, M., Tong, Y., Harezlak, J., & Rosenman, M. (in press) Insurance status of urban detained adolescents. Journal of Correctional Health Care.
  2. *Matthew C. Aalsma, Lauren C. Gudonis, G. Roger Jarjoura, Margaret J. Blythe, Yan Tong, Jaroslaw Harezlak, Marc B. Rosenman, The Consequences of Juvenile Detention Reform for Mental Health and Sexually Transmitted Infection Screening Among Detained Youth, Journal of Adolescent Health, 2012 Apr; 50(4):365-370. Available online 26 October 2011, ISSN 1054-139X, 10.1016/j.jadohealth.2011.08.013.
  3. *Tate DF, Sampat M, Harezlak J, Fiecas M, Hogan J, Dewey J, McCaffrey D, Branson D, Russell T, Conley J, Taylor M, Schifitto G, Zhong J, Daar ES, Alger J, Brown M, Singer E, Campbell T, McMahon D, Tso Y, Matesan J, Letendre S, Paulose S, Gaugh M, Tripoli C, Yiannoutsos C, Bigler ED, Cohen RA, Guttmann CR, Navia B; for the HIV Neuroimaging Consortium.  Regional areas and widths of the midsagittal cocorpus callosum among HIV-infected patients on stable antiretroviral therapies. J Neurovirol. 2011 Aug;17(4):368-379. Epub 2011 May 10.
  4. *Aalsma MC, Wiehe SE, Blythe MJ, Tong Y, Harezlak J, Rosenman MB. Mental Health Screening and STI Among Detained Youth. Journal of community health 2011 Apr;36(2):300-6
  5. *Harezlak J, Buchthal S, Taylor M, Schifitto G, Zhong J, Daar E, Alger J, Singer E, Campbell T, Yiannoutsos C, Cohen R, Navia B; the HIV Neuroimaging Consortium. AIDS. Persistence of HIV-associated cognitive impairment, inflammation, and neuronal injury in era of highly active antiretroviral treatment. AIDS, 2011 March 13; 25(5):625-33. PMID: 21297425
  6. *Cohen RA, Harezlak J, Gongvatana A, Buchthal S, Schifitto G, Clark U, Paul R, Taylor M, Thompson P, Tate D, Alger J, Brown M, Zhong J, Campbell T, Singer E, Daar E, McMahon D, Tso Y, Yiannoutsos CT, Navia B. J Cerebral metabolite abnormalities in human immunodeficiency virus are associated with cortical and subcortical volumes. J Neurovirol. 2010 Dec;16(6):435-44. Epub 2010 Oct 20.PMID: 20961212
  7. *Dydak U, Jiang Y-M, Long L-L, Zhu H, Chen J, Li W-M, Edden R.A.E, Hu S, Fu X, Long Z, Mo X-A, Meier D, Harezlak J, Aschner M, Murdoch J.B., Zheng W., In Vivo Measurement of Brain GABA Concentrations by Magnetic Resonance Spectroscopy in Smelters Occupationally Exposed to Manganese. Environ Health Perspect. 2011 Feb;119(2):219-24. Epub 2010 Sep 28. doi:10.1289/ehp.1002192
  8. *Hui SL, Perkins AJ, Harezlak J, Peacock M, McClintock CL, Johnston CC Jr. Velocities of bone mineral accrual in black and white American children. J Bone Miner Res. 2010 Jul;25(7):1527-35. PubMed PMID: 20200959.

10.  *Dewey J, Hana G, Russell T, Price J, McCaffrey D, Harezlak J, Sem E, Anyanwu JC, Guttmann CR, Navia B, Cohen R, Tate DF; HIV Neuroimaging Consortium. Reliability and validity of MRI-based automated volumetry software relative to auto-assisted manual measurement of subcortical structures in HIV-infected patients from a multisite study. Neuroimage. 2010 Jul 15;51(4):1334-44. Epub 2010 Mar 22. PubMed PMID: 20338250; PubMed Central PMCID: PMC2884380

11.  *Cohen RA, Harezlak J, Schifitto G, Hana G, Clark U, Gongvatana A, Paul R, Taylor M, Thompson P, Alger J, Brown M, Zhong J, Campbell T, Singer E, Daar E, McMahon D, Tso Y, Yiannoutsos CT, Navia B. Effects of nadir CD4 count and duration of human immunodeficiency virus infection on brain volumes in the highly active antiretroviral therapy era, Journal of Neurovirology, 2010 Feb;16(1):25-32.

12.  *Bravata DM, Daggett VS, Woodward-Hagg H, Damush T, Plue L, Russell S, Allen G, Williams LS, Harezlak J, Chumbler NR, A Comparison of Two Approaches to Screen for Dysphagia Among Acute Ischemic Stroke Patients: a Nursing Admission Screening Tool versus the NIH Stroke Scale, Journal of Rehabilitation Research and Development, 2009; 46(9): 1127-34

13.  *Harezlak J, Wu M, Wang M, Schwartzman A, Christiani D, Lin X, Biomarker Discovery for Arsenic Exposure Using Functional Data Analysis and Feature Learning of Mass-Spectrometry Proteomic Data, Journal of Proteome Research; 2008, 7:217-224; DOI: 10.1021/pr070491n

14.  *Harezlak J, Wang M, Christiani D, Lin X, Quantitative quality-assessment techniques to compare fractionation and depletion methods in SELDI-TOF mass spectrometry experiments, Bioinformatics, 2007, 23:2441-2448; DOI: 10.1093/bioinformatics/btm346

15.  Harezlak J, Coull BA, Laird NM, Magari S, Christiani DC, Penalized Solutions to Functional Regression Problems, Computational Statistics and Data Analysis, 2007, 51(10):4911--4925; DOI:10.1016/j.csda.2006.09.034

16.  Harezlak J, Naumova E, Laird NM  LongCriSP: a Test for Bump Hunting in Longitudinal Data, Statistics in Medicine, 2007;26:1383--1397; DOI: 10.1002/sim.2623

17.  Harezlak J, Tu W. Estimation of Survival Functions in Interval and Right Censored Data Using STD Behavioral Diaries,  Statistics in Medicine 2006; 25: 4053-4064, DOI: 10.1002/sim.2505

18.  Harezlak J, Ryan L, Giedd J, Lange N. Individual and population penalized regression splines for accelerated longitudinal designs, Biometrics 2005; 61:1037-1048

19.  Durban M, Harezlak J, Wand MP, Carroll RJ, Simple fitting of subject-specific curves for longitudinal data   Statistics in Medicine  2005: 24:1153-1167

20.  Rosenman MB, Kraft SK, Harezlak J, Mahon BE, Katz BP, Wang J, Arno JN, Syphilis Testing in Association With Gonorrhea/Chlamydia Testing During a Syphilis Outbreak  American Journal of Public Health. 2004; 94:1124-1126

21.  Hensel DJ, Fortenberry JD, Harezlak J, Anderson JG, Orr DP, A Daily Diary Analysis of Vaginal Bleeding and Coitus Among Adolescent Women. Journal of Adolescent Health, 2004; 34:391--394

22.  Khan AA, Khan A, Kroenke K, Harezlak J, Tu W, Physical Symptoms in Primary Care: Etiology and Outcome,  Psychosomatics 2003; 44:471-478

23.  Dunn DW, Austin JK, Harezlak J, Ambrosius WT, ADHD and epilepsy in childhood,  Developmental Medicine & Child Neurology, 2003; 45:50-54

24.  Harezlak J, Gao S, Hui SL. Illness-death stochastic model in the analysis of longitudinal dementia data,  Statistics in Medicine, 2003;  23:1465-1475

25.  Zhou X-H, Harezlak J. Comparison of Kernel Smoothing Methods for ROC curves, Statistics in Medicine 2002; 21:2045-2055

26.  Austin JK, Dunn DW, Caffrey HM, Perkins SM, Harezlak J, and Rose DF. Recurrent Seizures and Behavior Problems in Children with First Recognized Seizures: A Prospective study, Epilepsia, 2002; 43:1564-1573

27.  Bong CTH, Harezlak J,  Katz BP, Spinola SM. Men are more susceptible to pustule formation than women in the experimental model of  Haemophilus ducreyi infection, Sexually Transmitted Diseases 2002  29(2):114-118

28.  Fortenberry, JD, Tu W, Harezlak J, Katz BP, Orr DP,  Condom Use as Function of Time in New and Established Adolescent Sexual Relationships, American Journal of Public Health, 2002;  92:211-213

29.  Dunn D, Harezlak J, Ambrosius WT, Austin JK, Hale B. Teacher assessment of behaviour in children with new-onset seizures,  Seizure, 2002; 11:169-175

30.  Katz BP, Fortenberry DJ, Tu W, Harezlak J, Orr DP. Sexual Behavior among Adolescent Women at High Risk for Sexually Transmitted Infections. Sexually Transmitted Diseases 2001; 28:247-251

31.  Harezlak J, Heckman NE. CriSP: a Tool for Bump Hunting, Journal of Computational and Graphical Statistics,  2001; 10:713-729

32.  Austin JK, Harezlak J, Dunn DW, Huster GA, Rose DF, Ambrosius WT. Behavior Problems in Children before First Recognized Seizures. Pediatrics, 2001; 107:115-122.

33.  Moe SM, Zekonis M, Harezlak J, Ambrosius WT,  Gassensmith CM, Murphy CL, Russell RR, Batiuk TD, A Placebo Controlled Trial to Evaluate The Immunomodulatory Effects of Paricalcitol, (2001), American Journal of Kidney Diseases, 38(4):792-802

34.  Huberty TJ, Austin JK, Harezlak J, Dunn DW, Ambrosius WT, Informant Agreement in Behavior Ratings for Children with Epilepsy.  Epilepsy and Behavior, 2000; 1:427-435.

35.  Al-Tawfiq JA, Harezlak J, Katz BP, Spinola SM. Cumulative Experience with Haemophilus ducreyi 35000 in the Human Model of Experimental Infection. Sexually Transmitted Diseases, 2000; 27:111-114

36.  Chan K, Harezlak J, St-Aubin R, Vallee M, Case Study in Data Analysis: Vocalization Differences among Three Harp Seal Herds, (2000) , Canadian Journal of Statistics,  28(1):189-197


BIOS 546  Applied Longitudinal Data Analysis

BIOS 612  Modern regression methods

BIOS 646  Advanced Generalized Linear Models


Short courses at other institutions, including University of Porto, Portugal; Jagielonnian University, Krakow, Poland; Wroclaw University of Technology, Wroclaw, Poland.

Department of Biostatistics | 410 W. Tenth St., Suite 3000 | Indianapolis, IN 46202 | Ph: (317) 274-2661 | Fax: (317) 274-2678