Siu L. Hui

Degree PhD
Specialty Biostatistics
Professional Title
Distinguished Scientist, Regenstrief Institute; Professor Emerita of Biostatistics, Indiana University School of Medicine
Secretary Phone Number 317-630-8296317-274-9121 
Fax Number 317-274-9305
Expertise and Research Interests
Dr. Hui's research interest is in the design of observational studies, development of statistical methods and the application of innovative techniques to address biomedical and health services research questions. Her current interests include the use of large electronic health records to study practice patterns, health outcomes, and effectivenes of health care system implementations.
Professional Appointments
Assistant, Associate and Professor, Indiana University, School of Medicine, Indianapolis, Indiana 1981-2013, Distinguished Scientist, Regenstrief Institute, 2013-present.
Other Appointments and Professional Consultantships
Professional Organizations
Honors and Awards


RESEARCH INTERESTS: My current research interests are in the application of novel methdology to biomedical and health services research questions.  In particular, I am involved with the mining of large electronic health records databases to discover practice patterns and health outcomes, and to evaluate the effectiveness of health care system implementations.

1: Khan BA, Fadel WF, Tricker JL, Carlos WG, Farber MO, Hui SL, Campbell NL, Ely
EW, Boustani MA. Effectiveness of implementing a wake up and breathe program on
sedation and delirium in the ICU. Crit Care Med. 2014 Dec;42(12):e791-5. doi:
10.1097/CCM.0000000000000660. PubMed PMID: 25402299.

2: Daggy J, Xu H, Hui S, Grannis S. Evaluating latent class models with
conditional dependence in record linkage. Stat Med. 2014 Oct 30;33(24):4250-65.
doi: 10.1002/sim.6230. Epub 2014 Jun 17. PubMed PMID: 24935712.

3: Campbell NL, Cantor BB, Hui SL, Perkins A, Khan BA, Farber MO, Nazir A,
Garrett SL, Ely EW, Boustani MA. Race and documentation of cognitive impairment
in hospitalized older adults. J Am Geriatr Soc. 2014 Mar;62(3):506-11. doi:
10.1111/jgs.12691. Epub 2014 Feb 27. PubMed PMID: 24576177.

4: Torke AM, Sachs GA, Helft PR, Montz K, Hui SL, Slaven JE, Callahan CM. Scope
and outcomes of surrogate decision making among hospitalized older adults. JAMA
Intern Med. 2014 Mar;174(3):370-7. doi: 10.1001/jamainternmed.2013.13315. PubMed
PMID: 24445375; PubMed Central PMCID: PMC3947481.

5: Khan BA, Farber MO, Campbell N, Perkins A, Prasad NK, Hui SL, Miller DK,
Calvo-Ayala E, Buckley JD, Ionescu R, Shekhar A, Ely EW, Boustani MA. S100
calcium binding protein B as a biomarker of delirium duration in the intensive
care unit - an exploratory analysis. Int J Gen Med. 2013 Dec 2;6:855-61. doi:
10.2147/IJGM.S51004. eCollection 2013. PubMed PMID: 24324346; PubMed Central
PMCID: PMC3855164.

6: Nazir A, LaMantia M, Chodosh J, Khan B, Campbell N, Hui S, Boustani M.
Interaction between cognitive impairment and discharge destination and its effect
on rehospitalization. J Am Geriatr Soc. 2013 Nov;61(11):1958-63. doi:
10.1111/jgs.12501. Epub 2013 Oct 28. PubMed PMID: 24219196; PubMed Central PMCID:

7: Rosenman M, He J, Martin J, Nutakki K, Eckert G, Lane K, Gradus-Pizlo I, Hui
SL. Database queries for hospitalizations for acute congestive heart failure:
flexible methods and validation based on set theory. J Am Med Inform Assoc. 2014
Mar-Apr;21(2):345-52. doi: 10.1136/amiajnl-2013-001942. Epub 2013 Oct 10. PubMed
PMID: 24113802; PubMed Central PMCID: PMC3932461.

8: Xu H, Hui SL, Grannis S. Optimal two-phase sampling design for comparing
accuracies of two binary classification rules. Stat Med. 2014 Feb
10;33(3):500-13. doi: 10.1002/sim.5946. Epub 2013 Sep 4. PubMed PMID: 24038175.

9: Daggy JK, Xu H, Hui SL, Gamache RE, Grannis SJ. A practical approach for
incorporating dependence among fields in probabilistic record linkage. BMC Med
Inform Decis Mak. 2013 Aug 30;13:97. doi: 10.1186/1472-6947-13-97. PubMed PMID:
24001000; PubMed Central PMCID: PMC3766252.

10: Coté GA, Imler TD, Xu H, Teal E, French DD, Imperiale TF, Rosenman MB, Wilson
J, Hui SL, Sherman S. Lower provider volume is associated with higher failure
rates for endoscopic retrograde cholangiopancreatography. Med Care. 2013
Dec;51(12):1040-7. doi: 10.1097/MLR.0b013e3182a502dc. PubMed PMID: 24226304;
PubMed Central PMCID: PMC3830424.

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((Hui SL[au])  AND (Indiana [ad] AND University [ad]))

Department of Biostatistics | 410 W. Tenth St., Suite 3000 | Indianapolis, IN 46202 | Ph: (317) 274-2661 | Fax: (317) 274-2678